SMI空转发表文献汇总

所用技术作者合作单位区域文章标题发表期刊影响因子中科院分区发表年份发表月份研究内容样本种属样本类型疾病类型科室解读链接
CosMx SMI陈海泉复旦大学附属肿瘤医院上海Integrative spatial analysis reveals tumor heterogeneity and immune colony niche related to clinical outcomes in small cell lung cancerCancer Cell48.81 区20252整合空间分析揭示小细胞肺癌肿瘤异质性和与临床预后相关的免疫生态位人肺癌肿瘤组织小细胞肺癌肿瘤https://mp.weixin.qq.com/s/6dUEgvJXFAZXXR5HNxtvfg
CosMx SMI江一舟复旦大学附属肿瘤医院上海HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancerCell Metabolism30.91 区20259揭示肿瘤-巨噬细胞代谢互作影响三阴性乳腺癌免疫治疗疗效的新机制人肿瘤组织三阴性乳腺癌肿瘤https://mp.weixin.qq.com/s/T7Pgu34fAafLQSPxI1FRNw
CosMx SMI李燕中国医学科学院药物研究所北京Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous CraniopharyngiomasAdvanced Science13.61 区2025
12揭示造釉细胞型颅咽管瘤的代谢重塑与自噬激活人肿瘤组织腺瘤样颅咽管瘤肿瘤https://mp.weixin.qq.com/s/wS025RedywwIQO7avhlsYA
CosMx SMIMaxwell Y LeeStanford University School of Medicine美国Single-cell spatial transcriptomics uncovers niches that govern response to PD-1/PD-L1 blockade in cutaneous squamous cell carcinomaJournal for immunotherapy of cancer10.61 区20261SMI单细胞空间转录组结合组织芯片揭示cSCC免疫治疗响应的空间生态位机制人肿瘤组织样本皮肤鳞状细胞癌皮肤科https://mp.weixin.qq.com/s/N3ElhNUz0pSpB2ZxlxnODQ
CosMx SMI美国德克萨斯大学MD安德森癌症中心王凌华教授和Michael R. Green教授领导的合作团队美国Multi-modal spatial characterization of tumor immune microenvironments identifies targetable inflammatory niches in diffuse large B cell lymphomanature genetics29
202510描绘弥漫性大B细胞淋巴瘤独特的空间生态位及临床相关的免疫微环境特征人肿瘤组织弥漫大B细胞淋巴瘤肿瘤https://mp.weixin.qq.com/s/wTRflwGqGMEhXe6l6avN2w
CosMx SMIAnna Lasorella团队美国迈阿密大学米勒医学院美国Restraint of cancer cell plasticity by spatialhomotypic clusteringCancer Cell48.8
20259解析胶质母细胞瘤可塑性机制人肿瘤组织胶质母细胞瘤肿瘤https://mp.weixin.qq.com/s/abmg-3cHhN9iDNpp8mTXfg
CosMx SMIValerie Chew教授团队新加坡国立大学新加坡、德国Targeting Treg-fibroblast interaction to enhance immunotherapy in steatotic liver disease-related hepatocellular carcinomaGut25.8
20257揭示脂肪肝相关肝癌中的免疫抑制和微环境重塑人肿瘤组织脂肪性肝病相关肝细胞癌肿瘤https://mp.weixin.qq.com/s/yi77bGp7NwhTxBIM1of-bg
CosMx SMIShoba Amarnath研究团队纽卡斯尔大学英国、美国PD-1 receptor deficiency enhances CD30+Treg cell function in melanomaNature Immunology27.6
20256揭示PD-1缺失增强Treg的免疫抑制机制人肿瘤组织黑色素瘤肿瘤https://mp.weixin.qq.com/s/PL5MALxBl7VqlUFZ4nkwjg
CosMx SMI

Mariola Kurowska-Stolarska、Stefano

Alivernini

英国炎症性关节炎研究中心英国炎症性关节炎研究中心Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritisImmunity26.3
202412解析类风湿关节炎中的髓系树突状细胞人滑膜组织类风湿性关节炎风湿科https://mp.weixin.qq.com/s/NqA1vn4qf87aiPftoAkETg
CosMx SMILivnat Jerby教授美国斯坦福大学医学院美国Mapping spatial organization and genetic cell-stateregulators to target immune evasion in ovariancancerNat lmmunol27.7
202410SMI在专病队列中解决的科学问题：单细胞空间转录组揭示卵巢癌免疫逃逸的空间单细胞组织特征及细胞状态调节因子人卵巢癌肿瘤组织卵巢高分化浆液性癌肿瘤https://mp.weixin.qq.com/s/A7H52bPY8vFm0-EqtHidzw
CosMx SMINick R. Love美国加州大学戴维斯分校美国Melanoma progression and prognostic models drawn from single-cell, spatial maps of benign and malignant tumorsSci Adv13.6
20247黑色素瘤的进展和预后模型来自于良性和恶性肿瘤的单细胞、空间图人肿瘤（皮肤）黑色素瘤肿瘤https://mp.weixin.qq.com/s/9o1aQMIZNsfPSDyfeIcrag
CosMx SMIDenisenko, E.西澳大学澳大利亚Spatial transcriptomics reveals discrete tumour microenvironments and autocrine loops within ovarian cancer subclonesNat Commun16.6
20247揭示HGSOC亚克隆的高度异质性人肿瘤（卵巢）癌症肿瘤https://mp.weixin.qq.com/s/9bahzQMZAVgoV-2vEck94Q
CosMx SMIElvira Mennillo加州大学美国Single-cell and spatial multi-omics highlight effects of anti-integrin therapy across cellular compartments in ulcerative colitisNat Commun16.6
2024
2空间单细胞组学发现外周血靶细胞亚群的组织落脚点人结肠溃疡性结肠炎消化科https://mp.weixin.qq.com/s/_cbm2UBz-moPhBl3gdsXkA
CosMx SMIJoseph M. BeechemNanoString 研发科学家团队美国High-plex imaging of RNA and proteins at subcellular resolution in fixed tissue by spatial molecular imagingNat Biotechnol33.1
20229CosMx™ Spatial Molecular Imager（SMI）空间原位分子成像系统的化学原理、技术验证和应用领域人肿瘤（肺、乳腺）；细胞（细胞系）肿瘤肿瘤https://mp.weixin.qq.com/s/6dUEgvJXFAZXXR5HNxtvfg‍


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